منابع مشابه
Biological variation of glycohemoglobin.
The high precision of the results may enable single measurements instead of multiple determination, thereby reducing costs. The significantly lower values for ghrelin in citrate plasma may only partially (ϳ12%) be explained by dilution with the anticoagulating liquid in the tubes (118 Ϯ 15 L). The discrepancy between citrate plasma and serum was ϳ25%, a discrepancy that is too high for a recom...
متن کاملIntraindividual variation of glycohemoglobin: implications for interpretation and analytical goals.
Intraindividual variation (CVi) for glycohemoglobin (GHb) was estimated from serial measurements in patients with diabetes in either stable or variable clinical control. GHb determinations were performed by an affinity column procedure with an analytical imprecision of 4.9% (weighted average; GHb 8.2-14.7%). Within the groups of patients, both a short- (28-32 days) and long-term (approximately ...
متن کاملBiological Variation of Myeloperoxidase
Hansen KE, et al. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab 2004;89: 3152–7. 4. Souberbielle JC, Fayol V, Sault C, Lawson-Body E, Kahan A, Cormier C. Assay-specific decision limits for two new automated parathyroid hormone and 25-hydroxyvitamin D assays. Clin Chem 2005;51:395–400. 5. Singh RJ, Taylor RL, Reddy GS, Hollis BW...
متن کاملDiabetes and Glycohemoglobin
Introduction: Diabetes mellitus has long been recognized as a major cause of mortality and morbidity. The true frequency of the disorder is difficult to estimate because of differing diagnostic criteria but it is clearly the most common of the serious metabolic disorders occurring in roughly I to 4 percent of the U.S. population. It is a leading cause of mortality in this country, taking over 3...
متن کاملSources of variation in the column-chromatographic determination of glycohemoglobin (HbA1).
We studied the influence of many variables on the cation-exchange chromatographic determination of glycohemoglobin was minicolumns (HbA1) and with macrocolumns (HbA1a+b and HbA1c). Minicolumns are most sensitive to buffer composition. The best conditions are pH 6.78 and sodium, potassium, and phosphate concentrations of 54.8, and 36 mmol/L, respectively. In fact, there is no clear cut-off point...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2002
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/48.7.1116